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CORBETT BERRY

Personal Statement

I was born and raised in Salt Lake City, Utah. As most Utahns do, I gained an appreciation for the outdoors early on as well as enthusiasm for snowboarding, skiing and hiking. Following high school, I headed east and began my undergraduate studies in Biomedical Engineering at Case Western University in Cleveland. There, I discovered a passion for biomedical research which, in combination with a fascination with the human body, lead me to pursue enrollment in a combined MD/PhD program. I was fortunate enough to enter Drexel's MD/PhD program in Biomedical Engineering in 2012 following completion of my undergraduate studies.

Research Statement

We are interested in understanding how immune cells process external stimuli into a wide range of downstream events including cell activation and differentiation. In particular, we are interested in calcium signaling in lymphocytes. We want to understand how specific interactions between T cell receptors and antigen lead to distinct calcium signaling events. Furthermore, we strive to understand how these signals are decoded by lymphocytes to generate signal-specific cell fate decisions. We are investigating these mechanisms using a combination of state-of-the-art imaging techniques and computational analysis. Establishing an understanding of the role of calcium in lymphocyte development will provide us with insight to the etiology of autoimmunity and aberrant immune tolerance.

Projects

[2] Defining the role of calcium in natural regulatory T cell development (nTreg) development
 
[1] Modeling calcium signaling in lymphocytes
 

Awards

[3] Michelson Morley Competition in the Biological Sciences 2012, Case Western Reserve University
 
[2] Biomedical Engineering Scholar Award 2012, Case Western Reserve University
 
[1] Senior Project Presentation Award 2012, Case Western Reserve University
 

Posters/Presentations

[11] Berry, C.T., Melunis, J., Freedman, B., & Hershberg, U. 2014. CD28 modulation of TCR-induced calcium signaling: implications for nTreg development. Discovery Day 2014, Drexel University College of Medicine.
 
[10] Melunis, J., Berry, C.T., Doonan, P., Freedman, B., Hershberg, U. 2014. CD28 effects on calcium influx of thymocytes. Advancing the Health Care of Children. CHOP/Drexel/Hebrew University Collaborative Symposium.
 
[9] Melunis, J., Berry C., Doonan, P., Freedman, B., Hershberg, U. 2014. CD28 Effects on Calcium Influx of Thymocytes. IEEE Drexel Conference, Drexel University, Philadelphia, PA.
 
[8] Melunis, J., Berry C., Doonan, P., Freedman, B., Hershberg, U. 2014. CD28 Effects on Calcium Influx of Thymocytes. Systems Approaches in Immunology and Infectious Diseases, Santa Fe, New Mexico.
 
[7] Arko, L., Berry, C.T., Desai, A., Weaver, M.. 2014. Case series review of intradiploic epidermoid tumors of the cranium. American Association of Neurological Surgeons 82nd Annual Scientific Meeting.
 
[6] Berry, C.T., Melunis, J., Doonan, P., Freedman, B., & Hershberg, U. 2013. Decoding antigenic stimulation in thymocytes: effects of CD28 costimulation on calcium signaling. Medical Student Research Day 2013, Drexel University College of Medicine.
 
[5] Berry, C.T., Melunis, J., Doonan, P., Freedman, B., & Hershberg, U. 2013. Effects of CD3/CD4 activation alone, and when cross-linked to CD28, on calcium flux in thymocytes. Discovery Day 2013, Drexel University College of Medicine.
 
[4] Berry, C.T., Melunis, J., Doonan, P., Freedman, B., & Hershberg, U. 2013. Effects of CD3/CD4 activation alone, and when cross-linked to CD28, on calcium flux in thymocytes. American Physicians Scientists Association Regional Meeting 2013, Temple University.
 
[3] Berry, C.T., Jenkins, M.W., Lu, H., Shaw, K., Zhao, L., Chiel, H.J., & Rollins, A.M. 2012. Fourier domain optical coherence microscopy for optical detection of fast-spiking neural activity. Department of Biology, Neuroscience and Biomedical Engineering. Senior Project Presentations 2012.
 
[2] Berry, C.T., Jenkins, M.W., Lu, H., Shaw, K., Chiel, H.J., & Rollins, A.M. 2011. Phase-sensitive optical coherence tomography for optical detection of neural activity in Aplysia californica. Summer Program In Undergraduate Research, Case Western Reserve University.
 
[1] Berry, C.T., Sceniak, M., Sabo, S. 2010. Regulation of Synaptic Protein Transport by cAMP. Summer Undergraduate Research Program, Case Western Reserve University.
 

Publications

[2] Sceniak MP, Berry CT, Sabo SL. Facilitation of neocortical presynaptic terminal development by NMDA receptor activation. Neural Dev. 2012; 9: 8.
 
[1] Berry CT, Sceniak MP, Zhou L, Sabo SL. Developmental up-regulation of vesicular glutamate transporter-1 promotes neocortical presynaptic terminal development. PLoS One. 2012; 9.